Colchicine does not appear to negatively impact pregnancy outcomes, fertility, or lactation among men and women with FMF.

Bexarotene, a retinoid X receptor (RXR) agonist, is used to treat cutaneous T-cell lymphoma, and drug repositioning research has also been reported, despite warnings of teratogenicity. However, fetal ...

Did you know that certain medications can cause symptom of 'Teratogenicity'. Find these drugs listed on the page and be warned of similar symptoms as possible side-effects.

In addition to their therapeutic implications, these results constitute direct evidence that the teratogenicity of thalidomide may involve free radical-mediated oxidative damage to embryonic ...

Methotrexate (MTX) is a folate antagonist with known teratogenicity including abortifacient effects that interfere with DNA synthesis. We want to discuss on which findings teratogenicity is based and ...

Use of ponesimod in women with multiple sclerosis who are pregnant was not associated with a higher proportion of spontaneous abortions.

This guideline covers diagnosing and managing epilepsy in children, young people and adults in primary and secondary care, and referral to tertiary services. It aims to improve diagnosis and treatment ...

SYNOPSIS Thalidomide and its derivatives induce protein degradation via the ubiquitin ligase cereblon (CRBN), and leading to teratogenic phenotypes during embryogenesis. Here, the limb development ...

This repository contains supplemental code and data files for the publication "Machine learning on drug-specific data to predict small molecule teratogenicity" by Challa et al. - apchalla ...

Keywords: angiogenesis, 3D microfluidics, phthalimide derivative, Thalidomide, zebrafish embryo, teratogenicity Citation: Mercurio A, Sharples L, Corbo F, Franchini C, Vacca A, Catalano A, Carocci A, ...

Any maternal exposure to fluconazole during pregnancy — whether in low or high doses — may increase the risk for spontaneous abortion, and high-dose fluconazole during the first trimester may ...