A collaborative research team has successfully developed designer enzymes that exhibit both intrinsic and extrinsic functions ...

CRISPR-associated transposases (CAST) revolutionize enzyme engineering, enabling precise modifications for improved ...

The Stereoselectivity of Neighboring Group-Directed Glycosylation Is Concentration-Dependent Journal: Journal of the American Chemical Society Published: 2025-02-05 DOI: 10.1021/jacs.4c14402 ...

Enzyme and photocatalyst juggle 3-component reaction Researchers engineered an enzyme to wrangle multiple radicals with high stereoselectivity ...

Density functional theory (DFT) has been enacted to study the Diels–Alder reaction between 2,5-dimethylfuran (2,5-DMF), a direct product of biomass transformation, and acrolein and to analyze its ...

Corrigendum: Functional characterization and structural insights into stereoselectivity of pulegone reductase in menthol biosynthesisChanchan Liu1,5†, Qiyu G ...

Keywords: ene reductases, old yellow enzymes, protein engineering, biocatalysis, stereoselectivity, reduction Citation: Crotti M, Parmeggiani F, Ferrandi EE, Gatti FG, Sacchetti A, Riva S, Brenna E ...

Tryptophan dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) are the only two heme proteins that catalyze the oxidation reaction of tryptophan (Trp) to N-formylkynurenine. While human IDO is ...