To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The serine/threonine protein phosphatase 5 ...

Although the role of innate immune sensing pathways is well-studied in the pathogenesis of malignancies, whether they ...

The liver function in post-cardiac arrest brain injury is not known and was investigated in a pig model of global cerebral ...

Astrocytes in the brain exhibit significant regional diversity, but the mechanisms controlling their heterogeneity remain ...

Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...

Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...

MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...

RNA modulates transcription factor binding to DNA, though the subsequent effect on transcription remains unclear. The study ...

CaMKII activates the HRI/eIF2α signaling pathway and inhibits the proteotoxicity induced by proteasome inhibition through ...

How the hydrolytic activity of mitochondrial ATP synthase is modulated during brown adipose tissue (BAT) thermogenesis ...