Patients who used combinations of cardiovascular therapies experienced slower cognitive decline and fewer neuropathologies ...

Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are sporadic four-repeat tauopathies that have characteristic clinical and neuropathologic profiles, but also share ...

Neuropathologic studies show that the incidence of mixed co-pathology is high among neurodegenerative disorders and modifies disease symptoms and progression (Robinson et al, 2018). Therefore, ...

Beyond the massive cash drain and potential dependency possibilities, ‘heavy drinkers’ can face long-term effects that can ultimately damage the brain according to a new study out of Brazil titled ...

Heavy drinkers who have eight or more alcoholic drinks per week have an increased risk of brain lesions called hyaline arteriolosclerosis, signs of brain injury that are associated with memory and ...

The protein misfolding and aggregation of α-synuclein (α-Syn) into neurotoxic amyloids underlies the pathogenesis of neurodegenerative diseases such as Parkinson’s disease (PD). Emerging evidence ...

G-quadruplexes accumulate in the brain with aging and Alzheimer's disease, suggesting a new possible mechanism of neurodegeneration.

LATE-NC diagnostic criteria improve differentiation from Alzheimer's, addressing challenges in memory-loss syndromes and guiding therapeutic interventions.

A new guideline published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association summarizes best practices for specialists and primary care providers on how to evaluate patients ...

imageimageIn the early phase of Alzheimer’s disease, astrocytes are the primary source of APOE in the brain. This study examined the effects of astrocyte-derived human APOE isoforms in APOE-deficient ...

The Nature Index 2024 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their ...