Researchers have identified the enzyme PKN as a key factor in heart fibrosis, potentially leading to new treatments for heart ...

Experimental mRNA Cancer Vaccine Shows Potential for Advanced Stage Cancer Patients in Phase 1 TrialInterim data from the ...

The enzyme converts heart fibroblasts to myofibroblasts, putting the heart's integrity at risk. Deleting this enzyme reduced ...

The enzyme protein kinase N (PKN) has been implicated in a signaling cascade that causes heart fibroblast activation. A group ...

A team at Nagoya University Graduate School of Medicine has found that the enzyme protein kinase N (PKN) plays a role in ...

As society ages, the number of patients with heart failure is rapidly increasing. Excessive growth of fibrotic tissue in the ...

The gut microbiota and its functional metabolites play crucial roles in the development of intestinal fibrosis in patients ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The accumulation of myofibroblasts within the ...

Pliant Therapeutics' stock has seen declines due to concerns with trial results and competition. Read what could be next for ...

Myofibroblasts generate fibrotic scars after spinal cord injury (SCI). This is typically regarded as an impediment to nerve regeneration. Understanding the heterogeneous characteristics of ...