Pulmonary function remained stable -- and in some ways improved -- among patients with sickle cell disease (SCD) who ...

For the research, Ruhl and her team studied 97 patients with sickle cell disease who underwent a low-intensity, or non-myeloablative, blood stem cell transplant between 2004–2019 at the NIH's ...

One of Dr. Storb’s major scientific contributions is the non-myeloablative transplant. Non-myeloablative transplant, sometimes called "mini-transplant," involves minimal pre-transplant radiation. It ...

Discover new insights into the effects of haematopoietic cell transplant on pulmonary function in adults with sickle cell ...

A few days before Casgevy is infused, patients undergo myeloablative chemo to wipe out their bone marrow, removing unhealthy blood stem cells and making room for the new, edited versions.

Reduced-intensity conditioning regimes for HSCT candidates have similar short-term outcomes as HSCT candidates receiving myeloablative conditioning. Partial HLA-matched cord blood is a viable stem ...

To reduce duration of neutropenia and related sequelae in patients with nonmyeloid malignancies undergoing myeloablative chemotherapy followed by bone-marrow transplantation (BMT). To mobilize ...

Behçet's disease (BD) is a systemic large-vessel vasculitis characterized by a wide clinical spectrum including recurrent oral and genital ulcerations, uveitis, and vascular, neurological ...

Zevalin-mini allo; The major goal of this project is to conduct a Phase II trial evaluating the efficacy of Non-myeloablative 90Y-anti-CD20 Antibody, Fludarabine, Low-Dose total body irradiation (TBI) ...

Anti-Viral Central Memory CD8 Veto Cells is under clinical development by Cell Source and currently in Phase II for Sickle Cell Disease.