Blocking a key metabolic enzyme helps B cells fight liver tumors, revealing a new immunotherapy pathway for fatty liver–driven cancer in mice.

Prognosis is extremely poor for patients with head and neck squamous cell carcinoma (HNSCC), which accounts for around 90% of all head and neck cancer. Especially in the more aggressive subtype of ...

The 12-month price targets, analyzed by analysts, offer insights with an average target of $5.5, a high estimate of $7.00, and a low estimate of $5.00. Marking an increase of 31.89%, the current ...

T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by ...

The tumor microenvironment (TME) represents a highly complex system that encompasses cellular components (such as cancer cells, stromal cells, and immune cells) and non-cellular components (such as ...

HPVTIMER is a comprehensive web-based analysis tool based on the GEO database for HPV-associated cancers. HPVTIMER has four embedded analysis modules: Differential expression analysis module, ...

This review elucidates the dysfunction of B cells in tumor microenvironment, summarizes the discovery and mechanism of action of B cell ICs in tumors, and discusses urgent issues and future ...

Characteristics of the tumor microenvironment are likely to contribute to the aggressiveness of triple-negative breast cancer (TNBC) and the extremely poor prognosis of those who suffer it. By ...

Senescent macrophages have been overlooked for too long. They're not just passive markers of aging—they actively reshape the ...

Neutrophils are the most abundant type of white blood cells, critical for immune defense and inflammation control.

In a study published in Cell Biomaterials, a team led by chemical and nano engineers at the University of California San ...

A virus from humble black-eyed peas is showing extraordinary promise in the fight against cancer. Unlike other plant viruses, the cowpea mosaic virus (CPMV) can awaken the human immune system and ...