Variation in human mitochondrial DNA (mtDNA) has been used to infer the origin and migration patterns in human populations. mtDNA analysis has been focused mainly on the first hypervariable region ...

The hypervariable region, called apoB 3′ HVR, is located 75 bp downstream from the second polyadenylation signal at the 3′ end in the gene [1].

Archaeological evidence indicates that Birnirk peoples (AD 650–1300) are the proposed genetic ancestors of the Thule Inuit (AD 950–1400) and are potentially an intermediary population between the ...

While AbMAP's focus on hypervariable regions enhances its efficiency, the study also notes limitations, such as the potential underrepresentation of framework residues' roles in stability.