The hyperfunction theory, an alternative idea that has emerged in biogerontology in recent years, allows that molecular damage does occur. The theory, however, also holds that such damage probably ...

HYPERFUNCTION of differentiated cells occurs when the synthesis of proteins and nucleic acids is in excess of the requirement for normal cellular growth and proliferation1–7. Whether the ...

Dr. Mikhail Blagosklonny’s legacy: Hyperfunction theory and rapamycin “Blagosklonny’s work remains an enduring inspiration, paving the way toward treating aging as a modifiable condition.” ...

The hyperfunction theory of quasi-programmed aging explains why COVID-19 vulnerability is an age-dependent syndrome, linking it to other age-related diseases.

Immune thrombocytopenic purpura (ITP) is characterized by reduced platelet count secondary to immune-mediated destruction, this results in an increased bleeding risk. Autoantibodies binding to ...

Adrenocortical Hyperfunction in Association with Anaplastic Carcinoma of the Respiratory Tract Authors: Paul Bornstein, M.D., James P. Nolan, M.D., and David Bernanke, M.D. Author Info & Affiliations ...

Archive Androgenic Adrenal Hyperfunction in Acromegaly Authors: Nicholas Y. Lim, M.D., and Joseph F. Dingman, M.D. Author Info & Affiliations Published December 3, 1964 N Engl J Med 1964;271: 1189 ...

ROCHESTER, Minn.-A rare complication of Roux-en-Y gastric bypass surgery is hyperfunction of insulin-producing beta cells, which causes potentially life-threatening neuroglycopenia, say Mayo clinician ...