A collaborative research team has successfully developed designer enzymes that exhibit both intrinsic and extrinsic functions ...

A collaborative research team led by Associate Professor Yasunori Okamoto from the Exploratory Research Center on Life and Living Systems (ExCELLS ...

A mutant DJ-1 gene causes recessive Parkinson's disease, but the molecular mechanism of this process has not been well ...

The strategy for the linker synthesis is rapid (3–4 steps) and efficient (51–96% overall yield), and many of the linkers can be synthesized using a three-step one-pot strategy. Moreover, the linkers ...

To understand how DJ-1 hydrolyzes cyclic 3-phosphoglyceric anhydride—a highly reactive, toxic cellular metabolite—researchers ...