It is developmentally appropriate for young children to struggle with emotion regulation. Co-regulation and modeling emotion regulation strategies can help your child learn new skills. Positive ...

A new research paper was published in Volume 16 of Oncotarget on July 21, 2025, titled “Statins exhibit anti-tumor potential ...

Watermelon (Citrullus lanatus) is a nutrient-dense fruit rich in lycopene and L-citrulline, with demonstrated antioxidant, ...

Discover how men are using tools like the Oura Ring, IV therapy, red light therapy, and sleep syncing to optimize recovery, enhance sleep quality, and perform at their peak in 2025.

Similar to KMT2A -rearranged acute leukemia, NPM1 -mutant AML is highly dependent on the menin-KMT2A interaction. Disruption of this interaction, as achieved by menin inhibitors like revumenib, has ...

A surge in clinical trials investigating potential idiopathic pulmonary fibrosis therapies offers patients new hope, according to a recently published review.

Firstly, we found that RUNX2 isoform II-knockdown or overexpression could downregulate or upregulate the expression of GPX4 mRNA and protein, respectively (Figure 4-figure supplement 1A-D).

BACKGROUND: Circulating monocytes largely contribute to macrophage buildup in atheromata, which is crucial for clearing subendothelial LDLs (low-density lipoproteins) and dead cells; however, the ...

Collectively, these results suggest that GEFs can act as negative regulators of the ABA transduction pathway and potentially downregulate ROS signaling. How this effect can be reconciled with the role ...

OTX-2002 is a MYC-targeted Epigenomic Controller (MYC-EC), an mRNA drug substance encapsulated in a clinical lipid nanoparticle (LNP), designed to downregulate MYC expression pre-transcriptionally ...

Spironolactone, a steroidal mineralocorticoid receptor antagonist (MRA), has been used to treat patients with heart failure (HF) for more than half a century. Spironolactone improved outcomes in ...