A recently developed placental organoid offers new insights into the effects of SARS-CoV-2 infection on pregnant women and their children.

Single cell RNA-sequencing of distinct regions of the human placenta identifies a smooth chorion-specific cytotrophoblast population responsible for unique functions of the smooth chorion, including ...

While pEVTs and iEVTs were directly prepared from placental and decidua basalis tissues, respectively, purified placental cytotrophoblasts (CTBs) were used for establishing self-renewing TB-ORGs in ...

Extravillous trophoblasts are differentiated from cytotrophoblasts and invade the maternal decidua and maternal spiral arteries. Substantial crosstalk exists between maternal decidual cells and fetal ...

Essent Biologics™, a leading supplier of adult human-derived cell and scaffold materials, today announced it has entered into a global distribution partnership agreement with the Amnion Foundation, a ...

HAND2 regulates a distinct set of genes in endometrial stromal fibroblasts including IL15, a cytokine also exhibiting dynamic expression throughout the menstrual cycle and gestation, promoting ...

The placenta forms when embryo-derived cytotrophoblasts fuse to create multinucleated syncytiotrophoblasts, which mediate the maternal–fetal exchange of nutrients and gases.

Global transcriptomic profiling of cytotrophoblasts isolated from these cases, as compared to gestational age-matched controls, revealed numerous changes in gene expression involving diverse pathways, ...

Mononucleated cytotrophoblasts are undifferentiated progenitor cells, subjacent to the SynT, that differentiate and fuse to replenish the SynT. Other cytotrophoblasts differentiate into EVTs, which ...