Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

The San Diego Padres (88-66) take on the Chicago White Sox (36-118), who will be trying to halt a three-game losing streak, ...

Lenyn Sosa hit a tying two-run homer with two outs in the ninth inning, but the Chicago White Sox lost their 118th game when ...

Manny Machado’s San Diego Padres play the Chicago White Sox on Sept. 21 at 8:40 PM ET, and will see starting pitcher Chris ...

Everything you need to know about the San Diego Padres vs. Chicago White Sox game on Sept. 21, including how to watch info, ...

Preview the Sept. 21 matchup between the San Diego Padres and Chicago White Sox with odds over/under, game spread, betting ...

BOTTOM LINE: The Chicago White Sox, on a three-game losing streak, take on the San Diego Padres. San Diego is 43-36 in home games and 88-66 overall. The Padres have a 37-20 record in games when they ...

Davis Martin pitched well for the Sox in the loss, allowing three runs on seven hits with four strikeouts and two walks in ...

Who doesn’t want to be part of a momentous season — a good one or the worst one? I went to Guaranteed Rate Field Sunday to ...

Analyzing Friday’s Chicago White Sox at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

The Chicago White Sox are closing in on matching the 1962 New York Mets for the most losses in modern-day Major League ...

As the defeats continue to mount, the White Sox have joined the discussion of the most infamous baseball teams of all time.