Scientists have developed a chemical method to reverse aging in human cells without the need for genetic modification.

Safety and efficacy of a small-molecule c-Myc degrader WBC100 in solid tumors: A first-in-human, phase I trial.. If you have the appropriate software installed, you can download article citation data ...

Breast cancer is the most frequent malignancy among women worldwide, and all subtypes of breast cancer involve upregulation of the c-Myc gene, making it a compelling therapeutic target. G-rich regions ...

Viral-mediated Oct4 overexpression induces direct conversion of wildtype mammalian Müller glia to bipolar neurons, and this process is synergistically enhanced by loss of Notch signaling.

NEW YORK, May 08, 2025 (GLOBE NEWSWIRE) -- UTR Therapeutics Inc (UTRx Inc.), a drug development biotech company based in New York City, USA is pleased to announce a new milestone, the submission of an ...

In our pursuit of potent and selective G-quadruplex binders, herein we report a series of spironaphthalimide–pyrrolidine analogues that demonstrate the ability to stabilize c-MYC G4 formation and ...

The Yamanaka factors — specifically Oct4, Sox2, Klf4 and c-Myc — are transcription factors found throughout the scientific literature on cell reprogramming.