Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...

Hopes were high a decade ago, when a new class of drugs called BET inhibitors emerged for treating blood cancers and solid ...

New research has illustrated why a promising cancer drug doesn't work against some breast cancers – and has offered insights ...

However, specific acetylations can remove the positive charge on the lysine amino group that is acetylated, so the nucleosome "loses its grip" on the DNA. This modification results in a loosening ...

A BET inhibitor blocking the bromodomain of BRD4. This therapy has shown promise, but remains ineffective at treating breast ...

A breakthrough in dental care may soon spare you from the anxiety-inducing sounds of dental drills and the discomfort of root canal treatments. Researchers are exploring a novel method to combat ...

Thank you Eastman Chemical Co. for a new industry serving the entire North American market with a unique product, which has ...

The UAB researchers hypothesized that mouse models of BPD would show heightened levels of acetylated proline-glycine-proline, or Ac-PGP, an extracellular matrix-derived peptide, as had been seen in ...

The UAB researchers hypothesized that mouse models of BPD would show heightened levels of acetylated proline-glycine-proline, or Ac-PGP, an extracellular matrix-derived peptide, as had been seen ...

Release Agent Market The worldwide Release Agent Market holds an estimated portion of US$ 1036.4 million out of 2022 and is ...

This manuscript describes the impact of modulating signaling by a key regulatory enzyme, Dual Leucine Zipper Kinase (DLK), on hippocampal neurons. The results are interesting and will be important for ...