NOUS-209 induced robust, polyfunctional and durable CD8 and CD4 T cell responses against multiple frameshift peptide (FSP) neoantigens. Data support the further clinical development of NOUS-209 ...

After viral clearance, these specific T cells maintained a polyfunctional tissue-resident memory phenotype, highlighting their critical roles in infection control and long-term protection.

Reported Data Supports the Potential Extension of HD-MAP Vaccine Delivery to Oncology Indications Recently published data generated by researchers at The University of Queensland and Vaxxas shows ...

The results revealed that the LNP-mRNA vaccine induced a high frequency of polyfunctional, antigen-specific Th1 CD4+ T cells, an essential component of protective immunity against TB. This immune ...

Metabolic Stress Expands Polyfunctional, Proinflammatory Th17 Cells in Patients With Psoriatic Arthritis for Whom There is Interleukin-23–Independent Interleukin-17 Production ...

GA2-induced immunity correlated with polyfunctional CD4+ T cells and Vδ2+ γδ T cells, suggesting a pivotal role for late-liver-stage antigens. Unlike antibodies, these cellular responses were ...

Polyfunctional T cells also showed partial upregulation of Ki67, indicating a proliferative state (Figure 2E, Supplementary Figure S2D). In conclusion, restimulation ranging from 6 to 24 hours ...

These polyfunctional T cells expressed combinations of interferon-γ, TNF-α, and interleukin-2, with the preferential expression of TNF-α and interleukin-2 in CD4+ T cells and interferon-γ and ...

Flavio Coelho/Getty Images The most important strategic technology for 2025 and beyond is agentic AI, according to the latest forecast by tech analyst Gartner. "Agentic AI systems autonomously ...

Robots, Human-Machine Synergy, and (More) AI: Gartner's Top Trends for 2025 The firm's annual list is more focused on specific technologies than in recent years, but artificial intelligence once ...

Agentic AI will be the top tech trend for 2025, according to research firm Gartner. The term describes autonomous machine 'agents' that move beyond query-and-response generative chatbots to do ...