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Trastuzumab-containing chemotherapy is the recommended first-line regimen for human epidermal growth factor receptor 2 (HER2)–positive advanced gastric or gastroesophageal junction (G/GEJ) cancer. We ...
A new formulation of the drug paclitaxel may help overcome some common limitations of chemotherapy drugs, setting the stage ...
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News Medical on MSNRepackaged cancer drug boosts delivery to tumors, improves combination therapies
University of Arizona researchers devised a new method to deliver cancer chemotherapy drugs to pancreatic and breast cancer tumors more effectively and with less damage to healthy tissues than ...
Treatment with a paclitaxel-coated balloon led to better outcomes in patients with multilayer in-stent restenosis compared with conventional balloon angioplasty.
The addition of carboplatin to paclitaxel improved pathologic complete response and EFS with no increase in secondary malignancies among patients with triple-negative breast cancer, randomized ...
综述:细胞焦亡(Pyroptosis)与紫杉醇(Paclitaxel)在抗肿瘤作用中的治疗联系:最新综述 《Naunyn-Schmiedeberg's Archives of Pharmacology》:Therapeutic connections between pyroptosis and paclitaxel in anti-tumor effects: an updated review ...
Both paclitaxel and S-1 are effective against gastric cancer, but the optimal regimen for combined chemotherapy with these drugs remains unclear. This phase I/II study was designed to determine ...
Severe painful sensory neuropathy often occurs during paclitaxel chemotherapy. Since paclitaxel can activate mast cell and basophils, whereas quercetin, a polyphenolic flavonoid contained in ...
Paclitaxel was diluted in 250 mL of physiologic saline and infused over 3 hours. PLD was diluted in 250 mL of glucose 5% and infused over 60 minutes, following completion of carboplatin infusion.
The rates of clinical and angiographic restenosis were low for both drug-eluting stents, substantiating the results of previous studies. 1–5,7,9,10 A previous small, randomized trial involving ...
We conducted a randomized study to determine whether any of three chemotherapy regimens was superior to cisplatin and paclitaxel in patients with advanced non–small-cell lung cancer.A total of ...
Paclitaxel and other microtubule-binding drugs, such as the epothilones and the discodermolides, combat cancer by stabilizing a cancer cell's microtubules, thereby blocking cell division and ...
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