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波士顿 - 目前市值为877万美元、股价为6.96美元的微型生物科技公司Sensei Biotherapeutics, Inc. (NASDAQ: SNSE )将在即将于柏林举行的欧洲肿瘤内科学会大会上展示其solnerstotug单药及与Regeneron的PD-1抑制剂Libtayo (cemiplimab)联合用药的1/2期临床试验数据。根据 InvestingPro ...
Sensei Biotherapeutics, Inc. (NASDAQ: SNSE), a clinical stage immuno-oncology company focused on the discovery and ...
研究人员发现mTORC2缺失可降低肿瘤微环境酸度并减少PSGL-1表达,联合抗VISTA治疗显著抑制肿瘤生长,为LUSC的联合免疫治疗提供了新靶点。
Agonists of immune checkpoint modulators for treating autoimmune and inflammatory disorders have shown high potential in immunotherapy. P-selectin glycoprotein ligand 1 (PSGL-1) is known to exert ...
ALTB-268 operates through a unique mechanism of action, targeting PSGL-1, a key immune checkpoint regulator. It preferentially targets and downregulates chronically activated late-stage effector T ...
In a DSS-induced colitis model using human PSGL-1 knock-in mice, ALTB-268 reduced Disease Activity Index (DAI) scores, colon weight/length ratio, histopathologic inflammation scores, and colonic ...
PSGL-1/CD162抗体 由我公司独家生产销售,买就送50-100元话费优惠进行中,仅限定前1000名客户,相关标记抗体:辣根过氧化物酶标记抗体,生物素标记抗体,胶体金标记抗体, 红色罗丹明(RBITC)标记抗体,橙黄色PE标记,FITC绿色荧光。
近日,中山大学领衔的团队在一项发表于Science Immunology的研究中,揭示了P-选择素糖蛋白配体1(PSGL-1)在血癌免疫逃逸中的关键作用。
推荐 炎症、血栓和免疫失调是多种疾病的病理基础,现有动物模型存在局限。研究人员构建人 PSGL-1 转基因(hPSGL-1 TG)巴马小型猪模型,发现其出现炎症、心功能不全等,揭示 hPSGL-1 在相关病理中的关键作用,为研究和靶向治疗提供平台。