Positivity in cancer treatment, especially for children, is highlighted as a profoundly potent tool that enhances healing and ...

Lorlatinib is now being studied as part of the initial treatment for some children with high-risk neuroblastoma. Other drugs that target cells with ALK changes, such as ceritinib, and combination ...

He truly is a light to the world,” his mom said. “It definitely does put things in perspective all the little stuff does not matter.” ...

This strategy could also pave the way for treatments for cancers that are currently incurable, particularly in children. The first in vitro tests on pediatric neuroblastomas are indeed promising.

Why did you do this work? 1,645 children (aged 0–14) are diagnosed with cancer each year in the UK. These cancers tend to be quite different from cancers affecting adults, the most common being ...

Neuroblastomas are remarkably heterogeneous, with unique and variable biological and clinical features, including limited disease that can spontaneously regress and widespread disseminated disease (4, ...

Amplification of the MYCN gene in neuroblastomas is a potent biological marker of highly aggressive tumors, which are invariably fatal unless sound clinical management is applied. To determine the ...

BACKGROUND: Neuronal apoptosis plays an essential role in the pathogenesis of brain injury after subarachnoid hemorrhage (SAH). BAP1 (BRCA1-associated protein 1) is considered to exert pro-apoptotic ...

Ramani, P., et al. (2015) High Levels of Polo-Like Kinase 1 and Phosphorylated Translationally Controlled Tumor Protein Indicate Poor Prognosis in Neuroblastomas.

By leveraging transcriptional subtyping, we are now equipped to offer more precise prognosis and tailor therapies accordingly for patients with MYCN non-amplified neuroblastomas, potentially ...