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Maximum tolerated dose
除非受试者中开始出现无法耐受的副作用,此时的剂量称之为最大耐受剂量(Maximum tolerated dose,MTD)。若观察到额外的不可接受的毒性反应,则剂量递增试验终止,该毒性反应前的更小剂量可被定义为最大耐受剂量。以上临床试验假定 ...
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