Megakaryocyte count is a key diagnostic discriminator between severe aplastic anemia and lower risk hypoplastic MDS.

Keywords: aging, bone marrow endothelial cells, megakaryocyte, conditioned media, angiogenesis Click here to sign up for free Altmetric alerts about this article. AboutAging: ...

STRM.BIO presented the first preclinical data on the company's novel delivery platform for in vivo gene therapy that uses megakaryocyte-derived EVs to target bone marrow hematopoietic stem cells at ...

Background: The NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome has been described in both immune cells and platelets, but its role in the megakaryocyte (MK) lineage remains ...

Megakaryocyte Interaction With Different Bone Marrow Niches Mks interact with different hematopoietic and stromal cellular components while migrating between endosteal and central niches within the BM ...

Some emperipolesis may be seen in various disorders, including Immune thrombocytopenia. 1, 2 Aslan D postulated that, in ITP, emperipolesis contributes to megakaryocyte dysfunction and poor response ...

Megakaryocyte expansion was found in the peripheral blood mononuclear cell (PBMC) composition of patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and primary Sjögren ...

Megakaryocyte expansion was found in the peripheral blood mononuclear cell (PBMC) composition of patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and primary Sjögren ...

A 3D bone marrow niche that reproduces megakaryocyte differentiation and ex vivo platelet production from hematopoietic progenitors and iPSCs of thrombocytopenic patients predicts individual response ...