A novel protocol for the synthesis of monoprotected resorcinol N-methyliminodiacetate (MIDA) boronates was developed via the chemoselective deprotection of diprotected resorcinol MIDA derivatives with ...

imageimageThe mechanisms underlying the spatiotemporal control of Aurora-A kinase activity during mitosis are not yet determined. This study elucidates both the structure of the human Aurora-A:CEP192 ...

They’re chock-full of tricky stereocenters and hydroxyl groups that are prone to side reactions, which often require chemists to use tedious protection and deprotection steps to get to the ...

Stellate cell lactate transporter MCT1 significantly contributes to liver fibrosis through increased collagen 1 protein expression in vitro and in vivo.

Thioimidate Solutions to Thioamide Problems during Thionopeptide Deprotection Journal: Organic Letters Published: 2024-02-23 DOI: 10.1021/acs.orglett.4c00035 Affiliations: 1 Authors: 2 See more ...

Solid phase peptide synthesis (SPPS) is a technique for peptide synthesis. It can be defined as a process in which a peptide anchored by its C-terminus to an insoluble polymer is assembled by the ...

The synthetic route proposed includes thiol deprotection as the key step, see Figure 3. Inspired by the NCL approach, in this work we propose to use 2-aminothiols for the deprotection of the ...

While the deprotection‐by‐APC/C model does not readily explain how deprotection of centromeric cohesin is confined to meiosis II, it seems appealing for mammalian oocytes, which arrest at metaphase II ...

TITLE: Solvent-Free Mechanochemical Deprotection of N-Boc Group AUTHORS: Davor Margetić, Mateja Đud KEYWORDS: Green Chemistry, Mechanosynthesis, Boc Deprotection JOURNAL NAME: International Journal of ...

Electroreductive deprotection of the isonicotinyloxycarbonyl (iNoc) group from hydroxy, thiol, and amino groups was carried out in an electrochemical microreactor. The small distance of the platinum ...