(iii) Chemonucleolysis - injection of an enzyme into a bulging spinal disc in an effort to reduce the size of the disc Despite the critical importance of knowing whether surgery is beneficial, only ...

Lumbar Chymopapain Chemonucleolysis As early as 1961, Barr [14] in an article on the future of disc surgery, remarked that "we ought to be able to biochemically absorb some of the collagen tissue ...

Standard microdiscectomy Leg pain exceeding back pain, radicular signs and symptoms with corresponding imaging studies, failure to improve after conservative therapy- Automated percutaneous ...

《European Spine Journal》：Application of extracorporeal collagenase chemonucleolysis and combined intradiscal and extracorporeal collagenase chemonucleolysis via FLEX electrode in patients with lumbar ...

综述：腰椎间盘突出症管理中化学髓核溶解术与椎间盘切除术的比较：一项全面系统评价和荟萃分析 《Neurosurgical Review》：Comparison of chemonucleolysis and discectomy in the management of lumbar disc herniation: a comprehensive systematic review and ...

Chemonucleolysis of whole bovine IVDs is a useful tool providing researchers with a robust spectrum of degenerative changes and can be utilized for examination of therapeutic interventions.

Studies that evaluated plasma disc decompression and chemonucleolysis were also included, but the small number did not permit firm recommendations. Commendably, the authors carefully rated the ...

Evidence on plasma disc decompression and chemonucleolysis is limited by the low number of studies and small sample sizes. Large placebo controlled trials evaluating surgical treatment for sciatica ...

Chemonucleolysis of the nucleus pulposus by injection of condoliase is less invasive than surgery, but may cause disc degeneration. The purpose of the study was to examine outcomes of condoliase ...

Intradiscal oxygen-ozone chemonucleolysis met non-inferiority criteria and achieved similar rapid, significant clinical improvements as microdiscectomy in patients with single-level lumbar disc ...