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eBioMedicine:新研究发现富氏角膜内皮营养不良产生的关键机制
通过利用先进的单分子精度光学基因组图谱,研究者发现了极端水平的遗传不稳定性,从而确定了这种疾病的发展过程。这些发现仅限于FECD患者的角膜内皮细胞。这项研究还发现,体型和患者年龄都会影响遗传不稳定率。
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