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编辑推荐: 本研究揭示了线粒体三羧酸循环 (TCA)关键酶SUCLG1缺陷通过增加组蛋白琥珀酰化 (H3K122succ)水平,破坏BRD4与染色质的结合,从而抑制MYC等致癌基因转录的新机制。中国科学技术大学附属第一医院血液科Zhu Xiaoyu团队联合意大利特拉莫大学Domenico luso团队发现,SUCLG1缺失导致琥珀酰辅酶A (succinyl ...
A liquid fat medicine has shown significant promise in reversing major health complications of rare degenerative disease Ataxia-telangiectasia (A-T).
编辑推荐: 为解决水分亏缺条件下温室番茄产量和品质下降的问题,伊朗霍尔木兹甘大学研究人员开展壳聚糖及其衍生物(N-Succinyl和N,O-dicarboxymethylate)作为生物激发子的研究。研究发现N-Succinyl处理显著提高叶片ABA含量(增加16.6%),降低气孔导度(gs)和蒸腾速率(TR),同时提升净光合速率(Pn ...
PD-L 1 琥珀酰化改写黑色素瘤治疗格局 研究团队首次发现,黑色素瘤细胞中一个名为琥珀酰辅酶A(Succinyl-CoA)的代谢分子,竟是操控免疫检查点PD-L1 ...
Multiple copies of the genes coding for the α and β subunits of succinyl-CoA synthetase have been shown to exist in several species of Aspergillus and in Neosartorya fisheri, placing succinyl-CoA ...
Studies on the reaction mechanism of soybean callus succinyl CoA synthetase. phosphorylation of the enzyme on immobilized adenosine‐triphosphate and enzyme attached to a solid support.
Active enzyme sedimentation, sedimentation velocity, and sedimentation equilibrium studies of succinyl-CoA synthetases of porcine heart and Escherichia coli William T. Wolodko , Cyril M. Kay , and ...
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