In the U.S., incidence rates of some cancers have increased in 15- to 49-year-olds with concomitant increases in older age groups, suggesting that changes in risk factor prevalence and/or improvements ...

2018 Meetings Abstracts: Fifth AACR-IASLC International Joint Conference: Lung Cancer Translational Science from the Bench to the Clinic January 8–11, 2018; San Diego, CA Proceedings: AACR Annual ...

Hypoxia induces lactate production in neutrophils, leading to increased histone lactylation, and targeting this lactylation counteracts neutrophil-induced immunosuppression within glioblastoma tumors.

Abstract. This study presents national- and state-level prevalence of major modifiable cancer risk factors, human papillomavirus vaccination, and cancer screenings among US adults in the years during ...

AACR Journals Blood Cancer Discovery Cancer Discovery Cancer Epidemiology, Biomarkers & Prevention Cancer Immunology Research Cancer Prevention Research Cancer Research Cancer Research Communications ...

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Analysis of tumor transcriptomes from patients with renal cell carcinoma revealed that a tumor microenvironment featuring abundant tertiary lymphoid structures and minimal exhausted tissue-resident ...

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The EP3–ZNF488 master regulatory axis in cancer stem-like cells drives resistance to treatments like tumor treating fields, opening avenues for developing strategies to enhance therapeutic efficacy.

Galectin-1 is a key mediator of paclitaxel resistance in esophageal squamous cell carcinoma that can be targeted to improve taxane efficacy, suggesting broad therapeutic potential for treating various ...

Targeting KRAS in pancreatic cancer induces a resistant, highly differentiated cell state that serves as a reservoir for disease relapse, and cytoablative strategies aimed at this state offer a novel ...