2018 Meetings Abstracts: Fifth AACR-IASLC International Joint Conference: Lung Cancer Translational Science from the Bench to the Clinic January 8–11, 2018; San Diego, CA Proceedings: AACR Annual ...

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AACR Journals Blood Cancer Discovery Cancer Discovery Cancer Epidemiology, Biomarkers & Prevention Cancer Immunology Research Cancer Prevention Research Cancer Research Cancer Research Communications ...

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DKK1 is demonstrated to induce immunosuppressive polarization of macrophages, promoting tumor immune evasion in gastric cancer. The data showcase the potential of targeting DKK1, alone and in ...

ALDH1A1 enzyme activity induces MDSC expansion and triggers a procancer immune microenvironment to facilitate breast cancer progression, providing a novel therapeutic vulnerability in this disease.

A computational approach shows cryptic peptides as an abundant class of epitopes in different tumor samples. This approach can potentially be used to elucidate complete HLA-I immunopeptidomes and aid ...

In the U.S., incidence rates of some cancers have increased in 15- to 49-year-olds with concomitant increases in older age groups, suggesting that changes in risk factor prevalence and/or improvements ...

Abstract. Pancreatic cancer is an aggressive cancer characterized by high mortality and poor prognosis with survival of less than 5 years when advanced. Several studies showed that the ivermectin has ...

This review provides a comprehensive analysis of the current therapies targeting the TME, combining a discussion of the underlying basic biology with clinical evaluation of different therapeutic ...

Abstract. This study presents national- and state-level prevalence of major modifiable cancer risk factors, human papillomavirus vaccination, and cancer screenings among US adults in the years during ...

An acute myeloid leukemia CRISPR screen identified the histone acetyltransferase KAT6A as a repressor of differentiation that cooperates with the chromatin reader ENL to regulate leukemia ...