Pulmonary function remained stable -- and in some ways improved -- among patients with sickle cell disease (SCD) who ...

Behçet's disease (BD) is a systemic large-vessel vasculitis characterized by a wide clinical spectrum including recurrent oral and genital ulcerations, uveitis, and vascular, neurological ...

Discover new insights into the effects of haematopoietic cell transplant on pulmonary function in adults with sickle cell ...

Stem cell transplant is a promising treatment option for patients with myelodysplastic syndrome (MDS). Still, the decision to ...

Patients with undetectable measurable residual disease (MRD) tend to have similar transplantation outcomes after myeloablative or reduced-intensity conditioning; however, relapse risk is higher in ...

A few days before Casgevy is infused, patients undergo myeloablative chemo to wipe out their bone marrow, removing unhealthy blood stem cells and making room for the new, edited versions.

Donor sources included fully matched related (MRD), matched unrelated (MUD), and haploidentical (Haplo) donors. The conditioning regimen was designed to be reduced-toxicity myeloablative and did not ...

Reduced-intensity conditioning regimes for HSCT candidates have similar short-term outcomes as HSCT candidates receiving myeloablative conditioning. Partial HLA-matched cord blood is a viable stem ...

Anti-Viral Central Memory CD8 Veto Cells is under clinical development by Cell Source and currently in Phase II for Sickle Cell Disease.

For the research, Ruhl and her team studied 97 patients with sickle cell disease who underwent a low-intensity, or non-myeloablative, blood stem cell transplant between 2004–2019 at the NIH's ...