Pulmonary function remained stable -- and in some ways improved -- among patients with sickle cell disease (SCD) who ...

Discover new insights into the effects of haematopoietic cell transplant on pulmonary function in adults with sickle cell ...

For the research, Ruhl and her team studied 97 patients with sickle cell disease who underwent a low-intensity, or non-myeloablative, blood stem cell transplant between 2004–2019 at the NIH's ...

Behçet's disease (BD) is a systemic large-vessel vasculitis characterized by a wide clinical spectrum including recurrent oral and genital ulcerations, uveitis, and vascular, neurological ...

Anti-Viral Central Memory CD8 Veto Cells is under clinical development by Cell Source and currently in Phase II for Sickle Cell Disease.

Reduced-intensity conditioning regimes for HSCT candidates have similar short-term outcomes as HSCT candidates receiving myeloablative conditioning. Partial HLA-matched cord blood is a viable stem ...

He is also working to reduce toxicities and maximize the cancer-killing powers of transplanted immune cells. One of Dr. Storb’s major scientific contributions is the non-myeloablative transplant.

A few days before Casgevy is infused, patients undergo myeloablative chemo to wipe out their bone marrow, removing unhealthy blood stem cells and making room for the new, edited versions.

To reduce duration of neutropenia and related sequelae in patients with nonmyeloid malignancies undergoing myeloablative chemotherapy followed by bone-marrow transplantation (BMT). To mobilize ...

Zevalin-mini allo; The major goal of this project is to conduct a Phase II trial evaluating the efficacy of Non-myeloablative 90Y-anti-CD20 Antibody, Fludarabine, Low-Dose total body irradiation (TBI) ...