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11 天
PNAS丨基因突变致盲?探究ABCA4的表达与Stargardt黄斑变性
STGD1型Stargardt病是一种遗传性视网膜退行性疾病,与突变的ATP结合盒,亚科A,成员4(ABCA4)基因有关。STGD1是幼年黄斑变性最常见的形式,发病于儿童时期至成年早期或中期,可导致进行性、不可逆的视力障碍和失明,然而目前尚无有效的治疗方法。 2018年Tamara L ...
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Evaluation of fundus autofluorescence ımaging of diabetic patients without retinopathy
J R Soc Med. 2006;99(11):589-93.). Disruption of the metabolic activities of RPE cells leads to the induction of apoptosis and subsequent increase in RPE degradation products and lipofuscin granules ...
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