In critically ill children requiring mechanical ventilation, inhaled isoflurane shows sedation efficacy comparable to the routinely used intravenous sedative midazolam.

Sedana Medical AB (OSTO:SEDANA) reports robust growth and strategic progress, despite facing execution issues in key markets.

Intrathecal injection Under 2% isoflurane anesthesia, a 30G needle attached to a 25-μL Hamilton syringe was inserted into the intervertebral space between L5 and L6 spinal vertebrae in mice, as ...

The paradigm for sedating and administering analgesics to children who are critically ill and receiving mechanical ventilation in the paediatric intensive care unit (ICU) is changing. Advances in ...

These findings suggest that intravenous infusion of ketamine and lidocaine decreases the requirement for isoflurane during orthopedic surgery on anesthetized sheep.

Background and Purpose— Isoflurane, administered before or during cerebral ischemia, has been shown to exhibit neuroprotection in animal models of ischemic stroke. However, the underlying mechanism ...

The level of Cdh1 in the hippocampus was downregulated during isoflurane-induced neuroapoptosis. Cdh1-encoding lentivirus was transfected before isoflurane-treatment to increase the level of Cdh1. Our ...

In animal studies, reliable measures for depth of anesthesia are frequently required. Previous findings suggest that the continuous depth of anesthesia indices developed for humans might not be ...

Isoflurane is halogenated volatile ether used for inhalational anesthesia. It is widely used in clinics as an inhalational anesthetic. Neonatal hypoxic ischemia injury ensues in the immature brain ...

Neuroscience Testosterone alters isoflurane sensitivity Mouse research suggests a mechanism for controversial sex difference in response to anesthesia by Laurel Oldach January 18, 2024 ...