Hyperpolarization is a highly promising technique for improving the sensitivity of magnetic resonance chemical probes. Here we report [15N, D9]trimethylphenylammonium as a platform for designing a ...

The method, termed “Hyperpolarized MRI”, will allow imaging and visualization of key metabolic substrates in the heart and other organs (e.g., kidney, liver) via hyperpolarization of nuclear spins of ...

Metabolic MR imaging using hyperpolarized 13 C-pyruvate provides real-time assessment of pyruvate-to-lactate conversion, a process enhanced by PI3K/mTOR overactivation. We performed first-ever ...

Hyperpolarized MRI is based on the premise that cancer cells use and metabolize nutrients differently, and often at a faster rate, than normal cells do. Prior to the procedure, the molecules of a ...

The hyperpolarized fumarate is converted into malate by the addition of a heavy water molecule. This conversion eliminates the symmetry of the molecule, rendering it magnetic and detectable.

On December 23, 2022, the FDA granted approval for Polarean’s first drug device combination product, XENOVIEW TM (xenon Xe 129 hyperpolarized). 129 Xe MRI is also currently being studied for ...

A new diagnostic technique called hyperpolarized MRI provides a clear image of the brain’s metabolic activity. This can give important clues about whether a treatment is working in a shorter time ...

Hyperpolarizing carbon-13 nuclear spins in diamond holds implications for enhancing NMR/MRI sensitivity in applications related to molecular and biomolecular detection, diamond-based quantum ...

The FDA has approved xenon Xe 129 hyperpolarized, or Xenoview, to use along with MRI to analyze lung ventilation among adults and children aged 12 years and older, according to a manufacturer ...

RIT Professors Michael Kotlarchyk, George Thurston, and Pratik Dholabhai are developing a powerful next-generation technique, spin-modulated neutron scattering.

The U.S. FDA has approved Polarean Imaging plc’s drug-device combination product, Xenoview, for use with magnetic resonance imaging (MRI) in evaluating lung ventilation in adults and children aged 12 ...