Objective Homozygous alpha1-antitrypsin (AAT) deficiency increases the risk for developing cirrhosis, whereas the relevance of heterozygous carriage remains unclear. Hence, we evaluated the impact of ...

Homozygous deficiency of alpha1-atitrypsin is known to predispose to pulmonary emphysema. Measurement of the trypsin inhibitory capacity (TIC) of serum specimens from 28 relatives of a homozygous p ...

Learn more about paternal zygosity testing, which can help reveal if there is a risk of a fetus developing HDFN.

Novartis Pharmaceuticals Canada Inc. is pleased to announce the successful conclusion of negotiations with the pan-Canadian Pharmaceutical Alliance (pCPA) for the public reimbursement of Leqvio® ...

Mediator of RNA polymerase II transcription subunit 25 (MED25), a crucial component of the transcriptional coactivator complex, plays a significant role in t ...

Filings both for the obicetrapib monotherapy and obicetrapib plus ezetimibe fixed-dose combination submitted to EMA by our partner, Menarini, for treatment of adults with primary hypercholesterolemia ...

Company N.V. announced that the European Medicines Agency, EMA, has validated the Marketing Authorization Application, ...

Shot can act as a molecular linker between microtubules and actin during dendrite pruning, suggesting an intriguing role in non-centrosomal microtubule organization. However, the experimental evidence ...

Pure hypercholesterolemia is an inherited disorder that causes very high cholesterol levels, leading to coronary artery disease and heart attack at a young age.

CBSE Class 10 Science Half Yearly Sample Paper 2025 with solution. Explore the article to download the cbse class 10 sample ...