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生物通
11 天
分子对接辅助研究非诺贝特过渡金属包合与β-环糊精 ...
这项突破性研究聚焦降脂明星药物非诺贝特 (Fenofibrate)的溶解困境,巧妙运用分子对接 (molecular docking)技术作为导航仪,设计出双管齐下的增效方案:一方面让药物与铜乙酸酯 (copper acetate)在甲醇-水体系中"牵手"形成过渡金属复合物,另一方面又邀请β-环糊精 (β-CD)作为"分子胶囊"进行包合。 实验团队 ...
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