Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins.
Researchers have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization, each cell has the ...
Cells before and after TRAMs were introduced. TRAMs link a shuttle protein (red), and a target protein (green). Without the TRAM, the target protein resides in the nucleus (left), and upon TRAM ...