In the past 5–10 years there has been a growing trend for substituting conventional 5-fluorouracil with the oral prodrug of 5-fluorouracil, capecitabine, in chemotherapy regimens. This regimen ...

The Capecitabine market is experiencing growth due to increasing demand for effective chemotherapy treatments, particularly in colorectal and breast cancer. Key factors driving the market include ...

Background. A 66-year-old woman with metastatic mammary carcinoma, who was being treated with capecitabine, contracted a herpes zoster infection that was treated with the antiviral drug brivudin.

Capecitabine (Xeloda) is a type of oral chemotherapy often prescribed to treat metastatic breast cancer. It’s sometimes used alongside targeted therapy, or on its own if the cancer has stopped ...

PFS came in at 61.6% overall, at 62.9% in those with stable brain metastases, and at 59.6% in those with active brain ...

Enhertu is forecast to retain its dominant market position in the ADC landscape and reach global sales of $11.2bn by 2030.

Herrmann et al. compared the safety and efficacy of gemcitabine plus capecitabine (GemCap) with that of gemcitabine monotherapy in patients with pancreatic cancer. This phase III trial included ...

The US Food and Drug Administration (FDA) has approved a 420 mg dosage strength of Hercessi (trastuzumab-strf), a biosimilar to Herceptin (trastuzumab). Hercessi, a HER2/neu receptor antagonist, is ...

Besides carboplatin and cisplatin, other cancer drugs with limited availability include 5-fluorouracil, fludarabine phosphate, dacarbazine, methotrexate, amifostine, azacitidine, and capecitabine.

The COVID-19 pandemic has enabled researchers to show that a long course of radiotherapy given before surgery may be a better ...

Naomi Dempsey, MD, discussed developments in the HER2-positive breast cancer space, including personalized approaches, less ...

During the first cycle of capecitabine development, three concomitant drugs were found to affect 5-FU clearance. [5] Paracetamol and morphine increased 5-FU clearance by 26% and 41%, respectively ...