从临床角度来看，对多中心队列的生物信息学分析将 ESR2 确立为肺腺癌（LUAD）的重要预后生物标志物，其表达水平升高预示着总体生存率更低。这一临床相关性进一步证实了本实验结果，即 ERβ 促进转移性进展。

Sinopec Nanjing Engineering Corporation is undertaking petrochemical projects in Saudi Arabia, attracting local talents like ...

BANDAR SERI BEGAWAN, Aug. 1 (Xinhua) -- The Competition Commission of Brunei Darussalam (CCBD) has announced the enforcement of Section 21 and Section 23 of the Competition Act, which relate to the ...

BEIJING, July 22 (Xinhua) -- China is exploring the use of advanced technologies such as smart bionic hands and guide robots to improve the well-being of people with disabilities, ensuring that ...

LHASA, July 31 (Xinhua) -- From 2012 to 2024, Xizang has completed a total investment of 401.925 billion yuan (about 55.86 billion U.S. dollars) in fixed assets in highway transportation, and the ...

近日，福建医科大学/福建中医药大学研究人员合作共同在期刊《Cell Death Discovery》上发表了研究论文，题为“RBM17 promotes hepatocellular carcinoma progression by ...

Puromycin（嘌呤霉素，AbMole，M3637）在构建动物模型，尤其是肾病模型方面，有着重要的应用。以构建肾病动物模型为例，嘌呤霉素能够直接损伤肾小球上皮细胞。当给实验动物（如大鼠）注射嘌呤霉素后，它会作用于肾小球上皮细胞，使细胞骨架、细胞外 ...

中国政府2025年7月26日倡议成立世界人工智能合作组织，初步考虑总部设在上海。 The Chinese government on July 26, 2025 has proposed the creation of a global ...

综上所述，本研究揭示了ACSS2在ALD发病机制中的关键作用，即ACSS2通过CBP介导的组蛋白乙酰化调控 ...

PRAG1-FBXO11-SNAIL1调控轴的分子机制 研究人员发现PRAG1能与E3泛素连接酶FBXO11直接结合。正常情况下FBXO11通过泛素-蛋白酶体途径降解SNAIL1以抑制EMT，而PRAG1通过"劫持"FBXO11阻断其对SNAIL1的降解作用，从而稳定SNAIL1蛋白水平，最终促进EMT进程。

印度尼西亚推出创新抗震建筑设计，以应对俯冲带巨震风险。印尼气象、气候与地球物理局（BMKG，印尼语缩写）解释称，该新技术集成了先进的减震系统，能够抵御最高8.8级的地震。 据TV BRICS合作伙伴 新华社报道，BMKG局长德维 ...