This AI system can analyze up to one million DNA letters at once, predicting how tiny changes in noncoding regions trigger ...

Article Open access Published: 20 July 2016 Hypoxia-driven splicing into noncoding isoforms regulates the DNA damage response Danish Memon, Keren Dawson, Christopher SF Smowton, Wei Xing, Caroline ...

Campus News New blood test for noncoding RNA significantly improves cancer detection Assistant Professor of Biomolecular Engineering Daniel Kim and his lab are developing more accurate and powerful ...

New research shows modifying noncoding RNA with N6-methyladenosine allows the RNA exosome to recognize a specific noncoding RNA associated with the genomic site that encodes the heavy chain of ...

To identify noncoding mutations that are associated with functional effects in cancer, Dr. Ideker’s team turned back to TCGA data and carried out a systematic analysis of 930 tumors, integrating ...

"These noncoding RNAs may yield new biomarkers and therapeutic targets for cancer treatment, a potential opportunity for personalized medicine given their cell type-specific expression," added ...

Noncoding mutations contribute to autism risk Date: December 13, 2018 Source: Simons Foundation Summary: A whole-genome sequencing study of nearly 2,000 families has implicated mutations in ...

Noncoding RNAs (ncRNAs) are defined as RNAs that do not contain any open reading frames greater than 300 nucleotides (enough to code for 100 amino acids). Researchers once assumed “that proteins ...

The paper D.M. Anderson et al., “A micropeptide encoded by a putative long noncoding RNA regulates muscle performance,” Cell, 160:595-606, 2015. The transcript Eric Olson and his colleagues at the ...

Noncoding mutations in children with autism have greater impact scores, on average, than those in their unaffected siblings, the researchers found.