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Scientists from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences have ...
Scientists in China have created a special yeast strain that can produce large amounts of palmitoleic acid—an omega-7 fatty ...
研究人员针对NADPH氧化酶(NOXs)亚型选择性抑制难题,以非选择性抑制剂VAS2870为起点,通过苯并恶唑硫醇基团的功能化修饰,首次开发出NOX5亚型选择性共价抑制剂。该研究揭示了SNAr(亲核芳香取代)共价修饰释放活性基团的独特机制,为开发靶向NOXs亚型的选择性抑制剂提供了新策略,相关成果 ...
Energenesis Biomedical Co., Ltd. (TWSE: 6657), a clinical-stage biotechnology company focused on cellular energy restoration therapeutics, today announced the successful completion of its Phase I ...
Scientists from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences have ...
A comprehensive review by researchers at Teerthanker Mahaveer University highlights critical molecular pathways—including PKC activation, oxidative stress, and inflammatory cytokines—driving diabetic ...
A new study has identified an unexpected contributor to Alzheimer’s disease: glycogen, a complex sugar stored inside brain cells. While traditionally associated with muscles and the liver, glycogen ...
This Research Topic aims to explore how cellular metabolites (intermediates or end-products of metabolic processes) influence neuronal activity in both ...
2024年8月,欧洲心脏病学会(ESC)心力衰竭协会与心肌病工作组联合发布《糖尿病性心肌病临床共识声明》,重新定义了这一隐匿却致命的心血管并发症。新共识将糖尿病性心肌病定义为"在糖尿病存在的情况下出现的心肌收缩和/或舒张功能障碍",标志着临床诊疗从概 ...
在现代社会,生育健康正成为越来越多家庭关注的焦点。世界卫生组织最新数据显示,全球范围内每8对育龄夫妇中就有1对面临不育问题,而在我国,这一比例已攀升至12%-15%,其中男性因素导致的不育占比超过40%。令人担忧的是,临床检查中约60%的男性患者精子数量达标,但活力指标却低于正常标准——这些看似"合格"的精子,因为无法完成前向运动,往往成为备孕路上的隐形障碍。30岁的张先生就是典型案例,他和妻子备 ...
Patchoulol, a plant-derived sesquiterpene compound, is widely used in perfumes, cosmetics, and pharmaceuticals. Microbial production provides a promising alternative approach for the efficient and ...