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编辑推荐: 为解决酶促生物燃料电池因电极特异性导致的底物限制问题,研究人员设计了一种新型通用电极。该电极通过将铁氧还蛋白-NADP+氧化还原酶 (FNR)与细菌纤维素 (BC)、碳纳米管 (CNTs)和银纳米线 (AgNWs)复合固定化,成功耦合NADPH依赖性苹果酸酶或葡萄糖脱氢酶,实现了对苹果酸和葡萄糖的高效 ...
This shows that (a) NADP+ is taken up by the mitochondria across the inner membrane and into the matrix, and (b) NADP+-reducing activities of malate dehydrogenase and the NADP+-specific isocitrate ...
编辑推荐: 本研究揭示了2-脱氧-D-葡萄糖(2-DG)与NAD (P)H:醌氧化还原酶抑制剂ES-936联用可特异性增强癌细胞对高低线性能量转移(LET)辐射的敏感性,其机制涉及糖酵解抑制与氧化还原平衡破坏的双重作用。通过代谢分析、克隆形成实验及DNA修复效率检测,证实该组合能选择性降低癌细胞存活率并 ...
NAD+与NADP+是多种酶促氧化还原反应的辅酶。 1.生化研究;组织培养基的营养成分;药物为维生素B族,用于糙皮病及、等的治 疗。 2.是哺乳类动物必需的营养物。 水溶性较烟酸好,但易与维生素C生成复合物而结块。 用量30~mg/kg。
This Research Topic aims to explore how cellular metabolites (intermediates or end-products of metabolic processes) influence neuronal activity in both healthy and pathological states, with a ...
已知PTEN的缺失通过稳定G6PD来调节PPP和NADPH的产生, 医学高通量靶向代谢组学 显示,RIOK1过表达上调PPP相关代谢物,降低NADP+/NADPH比值(图3a-d)。
The University of Copenhagen is excited to announce NADMED as Tier 4 Sponsor of the 12th Aging Research & Drug Discovery Meeting, the world's largest conference on aging research in the ...
Oxidation-reduction state of free NADP+ during mixed-function oxidation in perfused rat livers—evaluation of the assumptions of near equilibrium by comparisons of surface fluorescence changes and ...
6th Annual Workshop on Metabolomics Sunday, July 22nd - Friday July 27th, 2018 Welcome to the 6th Annual Workshop on Metabolomics. The course is jointly sponsored by the National Institute of General ...
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