Because these mice have 'humanised' immune systems, we wouldn't then need to reengineer the antibodies to work in humans." The team treated mice with mAb1416, and 24 hours later exposed them to A.
Background In inflammatory bowel disease (IBD), a new biological therapy has recently been approved. Vedolizumab is a humanised IgG1 monoclonal antibody to α4β7 integrin that modulates gut lymphocyte ...