The novel PDE10A inhibitor CPL'36 offers a new mechanism of action and is both safe and effective for acute exacerbations of schizophrenia, new research suggests.

Extrapyramidal symptoms refer to involuntary movements, typically tremor, slowness, stiffness, loss of facial expressions and automatic movements, such as arm swing when walking.

Extrapyramidal effects are common when taking antipsychotic medications. Learn more about what these side effects are and what you should do about them.

Medications and their Potential to Cause Increase 'Extrapyramidal disorder' Developed by - Dr. M. Janani Priya, Pharm D Reviewed by - Dr. M. Sree Mohana Preetha, Pharm D Last Updated on Nov 16, 2023 ...

Extrapyramidal symptoms are a side effect of some medications such as antipsychotic drugs like dronabinol, risperidone, trandolapril, and others. These involuntary movements can be alarming and ...

The use of certain antidepressants may put patients at increased risk for extrapyramidal symptoms (EPSs), according to a large pharmacoepidemiologic study published in the Journal of Clinical ...

The scientists studied mice given haloperidol to mimic extrapyramidal symptoms seen in human patients. The mice were then given small-molecule kinase inhibitors to pharmacologically inhibit LRRK2.

Once daily, we assessed extrapyramidal symptoms using a modified Simpson–Angus Scale, a 5-item scale on which each item is scored from 0 to 4, with higher scores indicating worse extrapyramidal ...

One month later the patient had no depression, a clear reduction of the extrapyramidal symptoms, functional and cognitive improvement. Conclusion: An astonishing improvement occurred after the ...

Extrapyramidal symptoms associated with cyclic antidepressant treatment: a review of the literature and consolidating hypotesis J Clin Psychopharmacol 1997 17: 377–378 Article Google Scholar ...

Correspondence Archive Treatment of Extrapyramidal Symptoms Published June 15, 1961 N Engl J Med 1961;264: 1269 - 1270 DOI: 10.1056/NEJM196106152642420 ...