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新型支链多胺修饰二氢卟酚的光诱导抗菌活性研究
针对多重耐药菌这一全球健康威胁,研究人员通过将支链多胺引入天然二氢卟酚 (chlorin e6)分子,开发出新型光敏剂 (PS)。该研究采用APDT(抗菌光动力疗法)策略,显著提升了对金黄色葡萄球菌 (S. aureus)和铜绿假单胞菌 (P. aeruginosa)等革兰氏阳性/阴性菌的杀灭效果,为克服抗生素耐药性提供了新思路。
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