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强直性脊柱炎使用生物制剂:全身改善但局部不缓解怎么办?
导言强直性脊柱炎(AS)是一种慢性、免疫介导的炎症性疾病,主要累及脊柱和骶髂关节,也可以影响髋、膝等外周大关节。我国的发病率约为0.25%~0.3%,患者人数超300万,男性多于女性且发病高峰在20~30岁。早期主要表现为晨僵、下腰背痛、活动后缓解等 ...
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