Intravenous thrombolysis remains a standard treatment for acute ischemic stroke within 4.5 hours after onset. Vascular reocclusion may occur after intravenous thrombolysis and may be preventable ...

The author describes the scientific foundations and implications of a study on variant EPO and erythrocytosis.

After decades of undergoing epidemiologic study, prostate cancer remains an enigmatic disease; the only established risk factors are older age, family history of prostate cancer, and African ancest ...

This editorial explains the genetic basis of Pompe’s disease and other lysosomal storage disorders, as well as the foundations of enzyme-replacement therapy.

The landscape for genetically modified organisms is changing, thanks to sharp increases in the amounts and numbers of chemical herbicides applied to GM crops and the classification of two of the mo ...

To the Editor: The review article by Fasano (Jan. 23 issue)1 concerning human nutrition and hunger regulation omits the crucial role of autophagy, a cellular recycling process vital for maintaining ...

New AI-based software for generating patient notes purposely filters out social “chitchat,” but a primary care physician sees serious risks in that practice, for doctors and patients alike.

The current crisis in the United States is bigger than politics, and it deeply affects the health and lives of our patients and communities. Now is the time for physicians to harness their power an ...

A 60-year-old man with hypertension and bipolar disorder was incidentally found to have small cysts on his kidneys during MRI of the abdomen.

To the Editor: In the Blood Pressure Control Target in Diabetes (BPROAD) trial, Bi et al. (March 27 issue) 1 used the classic design of a prospective randomized trial with an intention-to-treat ...

This editorial explains the science behind a study of chimeric antigen receptor–expressing T cells to treat a series of 27 patients with neuroblastoma.