Oocytes are long-lived cells that require specialized adaptations to maintain their fitness. This study shows that human ...

These findings highlight the dual roles of antioxidants in cancer. Their impact depends on cancer type, stage, and genetic ...

Although centriolar satellites are increasingly being recognized as important subcellular structures that are tightly linked to centrosome functions, human disease, and cell differentiation, little is ...

On the occasion of its 40th anniversary, The EMBO Journal has launched the Catalysts program with the aim to give the next generation of group leaders a stronger voice in all aspects of publishing at ...

After being informed of a potential microduplication in Figure 1D, the journal contacted the authors for clarification. The ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

A common denominator for systems biology studies of a target organism is a high‐quality genome‐scale metabolic network reconstruction. A network reconstruction represents a biochemically, genetically, ...

Nociceptors, or pain‐sensitive receptors, are unique among sensory receptors in that their sensitivity is increased by noxious stimulation. This process, called sensitization or hyperalgesia, is ...

Glutaconyl‐CoA decarboxylase is a biotin‐dependent ion pump whereby the free energy of the glutaconyl‐CoA decarboxylation to crotonyl‐CoA drives the electrogenic transport of sodium ions from the ...

In mammals, maintenance of energy and nutrient homeostasis during food deprivation is accomplished through an increase in mitochondrial fatty acid oxidation in peripheral tissues. An important ...

Lung adenocarcinoma (LUAD) continues to pose a significant mortality risk with a lack of dependable biomarkers for early noninvasive cancer detection. Here, we find that aberrant lipid metabolism is ...

The forkhead transcription factors are winged helical proteins first known for their role in development. Each of the more than 90 members of the forkhead family contains a conserved DNA binding ...