Gene transfer into the peritoneal cavity by nonviral methods may provide an effective therapeutic approach for peritoneal diseases. Herein, we investigated the feasibility and the effectiveness of ...

Drug delivery systems can alter drug clearance from the peritoneal cavity and drug toxicity profiles. For example, IP injection of cisplatin-loaded polymeric microspheres (100–200 µm, which ...

The peritoneum, the lining of the abdominal cavity, is frequently involved in advanced-stage cancers, including gastric, colon, pancreatic, and ovarian cancers.

Peritoneal cancer is difficult to treat and has a poor survival prognosis. But a new and effective nanomedicine delivery system is offering some hope.

The ratios of drug AUC in the peritoneal cavity and AUC in systemic blood are 12 for cisplatin, 10 for carboplatin, 65 for melphalan, 65 for etoposide, 75 for mitomycin C, 367 for 5-fluorouracil ...

Prognostic significance of free peritoneal tumor cells in the peritoneal cavity before and after neoadjuvant chemotherapy in patients with gastric cancer undergoing a potentially curative resection.

Evidence has been secured that when colon bacilli or streptococci are injected in large numbers into the peritoneal cavity of dogs or rabbits, they begin to enter the blood through the thoractic duct ...

Purpose: Malignant mesothelioma (MM) arising in the peritoneal cavity is a rare neoplasm characterized by peritoneal progression and for which there are limited therapeutic options. We evaluated the ...

In the last 30 years Basingstoke and North Hampshire Hospital has become a world leader in this type of cancer. PMP originates in the appendix and spreads throughout the peritoneal cavity, which is ...

Peritoneal cancer is a form of cancer that affects the peritoneum, a thin layer of tissue that lines the abdominal cavity and internal organs. It is not common, with around about 7 cases occurring ...