A multiepitope mRNA construct encoding ten epitopes derived from the murine B.16.F10 melanoma cell line was tested in mice. The study applied three 5 µg doses of LNP-formulated B.16 mRNA ...

Using Gromacs 2021.5, this PCA was applied to complexes formed by multi-epitope vaccines with Toll-Like Receptor-2 (TLR-2), and TLR-4, B7-1, B7-2, projecting the results onto two dimensions.

Immunologic and Clinical Outcomes of Vaccination With a Multiepitope Melanoma Peptide Vaccine Plus Low-Dose Interleukin-2 Administered Either Concurrently or on a Delayed Schedule Authors: Craig L.

New multi-epitope HIV-1 vaccine based on virus-like particles engineered to enhance immune response Feb. 7, 2025 ...

Successful safety review of data from glioblastoma Phase 1 Part A with multiepitope cancer vaccine candidate, CVGBM, enables progressing to Part B with expected start mid-2024 ...

Study: Lymph node targeted multi-epitope subunit vaccine promotes effective immunity to EBV in HLA-expressing mice. Image Credit: Kateryna Kon/Shutterstock.com Background Epstein-Barr virus (EBV ...

Adaptive multi-epitope targeting and avidity-enhanced nanobody platform for ultrapotent, durable antiviral therapy. Cell, 2024; DOI: 10.1016/j.cell.2024.09.043 ...

Purpose A phase II trial was performed to test whether systemic low-dose interleukin-2 (IL-2) augments T-cell immune responses to a multipeptide melanoma vaccine. Forty patients with resected stage ...