资讯

为解决抗癌药物体内稳定性差、毒性高及缺乏靶向性等问题,研究人员开发了基于PEG稳定化脂质盘(lipodisks)的共递送系统,用于同时装载化疗药物(DOX/SN-38)和膜溶解肽(melittin)。
为解决乳腺癌治疗难题,研究人员探究蜂毒肽(Melittin)- 果胶制剂抗癌效果,发现其抗癌活性优越,意义重大。
This time-lapse image from a confocal microscope shows what happens over 6.5 minutes as a synthetic membrane-enclosed structure called a giant unilamellar vesicle (GUV) is exposed to melittin, the ...
Melittin is a widely studied membrane active peptide, or MAP, that interacts with cell membranes. Researchers are interested in melittin and other MAPs from animal venom because of their potential ...
These include melittin, a peptide found in the European honey bee’s venom that has attracted scientists’ attention since the 1950s. It’s now believed to confer a host of benefits, including immune ...
Melittin and honeybee venom were studied for their anti-cancer properties and showed they decreased the viability of triple-negative breast cancer cells and HER2-enriched breast cancer cells, Dr ...
In addition to its cytotoxic effects, melittin can also inhibit molecules that are overexpressed in cancer cells, effectively halting the spread of malignant growth.
Honeybee venom induces cancer cell death in hard to treat triple-negative breast cancer with minimal effect on healthy cells, new research finds.
"We found both honeybee venom and melittin significantly, selectively and rapidly reduced the viability of triple-negative breast cancer and HER2-enriched breast cancer cells,” she says.
Thus, Melittin's targeted inactivation of inflammation may hold the key to the anti-arthritic effects of bee venom.