摘要2024年欧洲呼吸学会发布了国际上首部关于肺泡蛋白沉积症（PAP）诊断和管理的指南。该指南针对PAP的定义、临床诊断流程、治疗方案、疗效评估和未来研究方向等多个方面进行阐述，给出了较为明确的推荐意见。本文将从上述几个方面介绍该指南的要点，旨在帮助 ...

Pulmonary alveolar proteinosis is a rare disorder in which lipoproteinaceous material accumulates within alveoli. 1 The clinical course of the disease is variable, ranging from respiratory failure ...

Pulmonary alveolar proteinosis is caused by defective signaling by the GM-CSF receptor, usually owing to a genetic deficiency that results in the diminished expression or function of the α or ...

Autoimmune pulmonary alveolar proteinosis affects about 7 of every 1 million people. It typically affects adults aged 30 to 40 years, but children can get it as well. This disease affects two to ...

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood and is broadly divided into two main subgroups—alveolar (ARMS) and embryonal (ERMS)—on the basis of morphological ...

We therefore want to understand how pollution affects this specific and very delicate body part. The alveolar epithelium is made up of several different types of cells, each with a specific job.

Researchers have found that antigen-specific killer T cells (CD8+ T cells) rapidly expand in the lungs when primed by antigen-presenting lung-resident alveolar macrophages (AMs). This interaction ...

Albeit alveolar echinococcosis is an uncommon disease, its presentation can be very serious, leading to a case fatality rate of 50% or greater in symptomatic cases.

Alveolar macrophages need to be stimulated by granulocyte-macrophage colony-stimulating factor (GM-CSF) to function properly in clearing surfactant, but in aPAP, GM-CSF is neutralized by ...